Supplemental parenteral nutrition: decisions based on weak evidence

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Enteral and parenteral nutrition: evidence-based approach.

Nutrition support for patients in hospital has become an essential form of therapy. Total parenteral nutrition (TPN) was the preferred way of giving nutrition to hospital patients for many years but enteral nutrition (EN) is now the preferred route. EN is believed to promote gut function and prevent translocation of intestinal bacteria, thus reducing the incidence of sepsis in critically ill pa...

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Intradialytic Total Parenteral Nutrition (IDPN): Evidence-Based Recommendations

INTRODUCTION Protein-energy malnutrition (PEM) is very common among patients with end-stage renal disease (ESRD) undergoing maintenance hemodialysis therapy (note: the term ESRD here is used to refer specifically to patients undergoing thrice weekly chronic hemodialysis) (1). Owing to different definitions of PEM and different patient populations that have been studied, the prevalence of PEM in...

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Parenteral nutrition.

Nutritional insufficiency, leading to early growth deficits has long-lasting effects, including short stature and poor neurodevelopmental outcomes. Early enteral feeding is commonly limited by immaturity of gastrointestinal motor function in preterm neonates. To ensure that a stressed premature infant receives an adequate but not excessive amount of glucose, the amount of carbohydrate delivered...

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Comparison the inflammatory effects of early supplemental parenteral nutrition plus enteral nutrition versus enteral nutrition alone in critically ill patients

BACKGROUND AND THE PURPOSE OF THE STUDY It is believed that enteral nutrition (EN) support is the preferred route as compared to parenteral nutrition (PN). Critically ill patients on EN receive less than 60% of their metabolic requirements. To meet patients' calorie goal addition of PN to EN was proposed. This study was conducted to determine whether supplemental PN have any difference with EN ...

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Total parenteral nutrition-induced liver dysfunction: evidence and pathogenesis

Results: Varied injuries to the liver are induced clinically and experimentally by progressive deterioration after a longer period of TPN infusion. The mechanisms of cholestasis and fibrosis in pathological changes include alteration of trace elements in hepatocytes, metabolic disturbance of fatty acid, calorie overload, lithocholate effect, sepsis, etc. The administration route of TPN is exclu...

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ژورنال

عنوان ژورنال: ESMO Open

سال: 2020

ISSN: 2059-7029

DOI: 10.1136/esmoopen-2020-000831